β-Thalassemia · cohort
Testing cohort · n = 30
source: seed · 4 treatment arm(s) · synthetic / no PHI
Cohort source
active · seed (30)Governance: this demonstrator is synthetic / NO_PHI. Uploading a real cohort requires Thailand PDPA consent + IRB approval (see /pdpa). Upload only synthetic or de-identified data here.
patients
30
treatment arms
4
proceed-now
4
needs review
26
Cohort table
Per-patient · seed cohort
Research preview
| ID | Arm | HBB genotype | α-thal status | BCL11A HbF QTL dose | HBS1L-MYB HbF QTL dose | Readiness |
|---|---|---|---|---|---|---|
| SYN-001 | GT-CRISPR-BCL11A | β0/βE | normal | 2 | 2 | proceed-now |
| SYN-002 | HSCT-MUD | β0/βE | -α/αα | 1 | 2 | optimize-first |
| SYN-003 | HSCT-MUD | β0/βE | normal | 1 | 1 | more-data-required |
| SYN-004 | HSCT-MSD | β0/β0 | normal | 0 | 0 | redesign-protocol |
| SYN-005 | GT-lentiviral | β0/βE | normal | 2 | 1 | proceed-now |
| SYN-006 | HSCT-MSD | β+/β0 | -α/αα | 0 | 1 | proceed-now |
| SYN-007 | HSCT-MSD | β+/β+ | -α/-α | 0 | 1 | redesign-protocol |
| SYN-008 | HSCT-MSD | β0/β0 | -α/-α | 1 | 1 | redesign-protocol |
| SYN-009 | HSCT-MSD | β0/βE | --/αα | 1 | 0 | redesign-protocol |
| SYN-010 | HSCT-MUD | β+/β0 | normal | 2 | 0 | redesign-protocol |
| SYN-011 | GT-lentiviral | β0/βE | -α/-α | 2 | 0 | redesign-protocol |
| SYN-012 | GT-lentiviral | β+/β0 | -α/αα | 0 | 1 | more-data-required |
| SYN-013 | HSCT-MSD | β+/β0 | normal | 2 | 1 | redesign-protocol |
| SYN-014 | HSCT-MUD | β+/β0 | normal | 2 | 1 | redesign-protocol |
| SYN-015 | GT-CRISPR-BCL11A | βE/βE | --/αα | 1 | 0 | proceed-now |
| SYN-016 | GT-CRISPR-BCL11A | β+/β0 | -α/αα | 2 | 1 | redesign-protocol |
| SYN-017 | HSCT-MUD | βE/βE | -α/-α | 1 | 2 | optimize-first |
| SYN-018 | GT-CRISPR-BCL11A | β0/β0 | normal | 1 | 2 | redesign-protocol |
| SYN-019 | HSCT-MUD | β+/β0 | normal | 1 | 0 | redesign-protocol |
| SYN-020 | HSCT-MUD | βE/βE | -α/αα | 2 | 2 | redesign-protocol |
| SYN-021 | HSCT-MSD | β0/β0 | -α/αα | 0 | 2 | more-data-required |
| SYN-022 | GT-lentiviral | β+/β0 | --/αα | 2 | 1 | redesign-protocol |
| SYN-023 | GT-CRISPR-BCL11A | β+/β0 | --/αα | 0 | 1 | redesign-protocol |
| SYN-024 | HSCT-MUD | β0/βE | -α/αα | 1 | 1 | redesign-protocol |
| SYN-025 | HSCT-MUD | β0/β0 | normal | 1 | 0 | redesign-protocol |
| SYN-026 | GT-CRISPR-BCL11A | β+/β0 | -α/-α | 1 | 1 | redesign-protocol |
| SYN-027 | HSCT-MUD | β0/βE | -α/-α | 0 | 2 | redesign-protocol |
| SYN-028 | GT-lentiviral | β0/β0 | normal | 1 | 0 | redesign-protocol |
| SYN-029 | HSCT-MUD | β+/β+ | -α/-α | 0 | 1 | redesign-protocol |
| SYN-030 | GT-lentiviral | βE/βE | -α/αα | 1 | 0 | more-data-required |
This interface presents outputs of a research-preview prediction model. It is not a regulated decision-support tool. Predictions come from one calibrated XGBoost classifier per endpoint, fitted on a synthetic-labeled cohort (no PHI; labels anchored to published base rates) and evaluated on a held-out synthetic test split. Not pre-registered; not externally validated.